Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM388637'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM388637(AZD1858 MCJ001- SS | US9944618, Compound ID No. 17...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:SERT: This protocol was designed to measure inhibition of uptake by the human serotonin transporter. The reagents were human SERT (HEK293F) cells, fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5WBRUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM388637(AZD1858 MCJ001- SS | US9944618, Compound ID No. 17...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Binding affinity to human SERT expressed in HEK293 cells after 60 mins in presence of [3H]imipramine by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7K8MPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM388637(AZD1858 MCJ001- SS | US9944618, Compound ID No. 17...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Binding affinity to human SERT expressed in HEK293 cells after 60 mins in presence of [3H]imipramine by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7K8MPubMed