Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50010874'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50010874(1-(1-(4-chlorophenyl)-2-(dimethylamino)ethyl)cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Inhibition of 5HT uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16PBPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010874(1-(1-(4-chlorophenyl)-2-(dimethylamino)ethyl)cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4WCMPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010874(1-(1-(4-chlorophenyl)-2-(dimethylamino)ethyl)cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of 5HT uptake at rat brain SERTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16PBPubMed