Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50029154'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50029154(5-Fluoro-3-piperidin-4-ylmethyl-1H-indole | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z3ZPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50029154(5-Fluoro-3-piperidin-4-ylmethyl-1H-indole | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of uptake of 5-HT in rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5NQDPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029154(5-Fluoro-3-piperidin-4-ylmethyl-1H-indole | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:In vivo inhibition of uptake of 5-HT in human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5NQDPubMed