Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50073436'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Binding affinity for serotonin transporter expresed in LCK PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7GRZPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)copy SMILEScopy InChI
Affinity DataKi:  0.0970nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N22RJPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)copy SMILEScopy InChI
Affinity DataKi:  0.0970nMAssay Description:Binding affinity to SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V989DMPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)copy SMILEScopy InChI
Affinity DataKi:  0.0970nMAssay Description:In vitro binding affinity of the compound against Serotonin transporter (SERT) from LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition of [125I]IPT uptake at SERT (unknown origin) expressed in LLC-PK1 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V989DMPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]IPT from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0M3JPubMed