Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50091097'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Centre for Addiction and Mental Health

Curated by ChEMBL
LigandPNGBDBM50091097(3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity on cloned Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J67G4WPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50091097(3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N22RJPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Centre for Addiction and Mental Health

Curated by ChEMBL
LigandPNGBDBM50091097(3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Binding affinity for serotonin transporter expresed in LCK PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7GRZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Centre for Addiction and Mental Health

Curated by ChEMBL
LigandPNGBDBM50091097(3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  1.12nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9371GPubMed