Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50150105'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50150105(CHEMBL124069 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  0.470nMAssay Description:Inhibition of serotonin reuptake in SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5WP7PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150105(CHEMBL124069 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  0.470nMAssay Description:Binding affinity against serotonin transporter in rat cortical tissues using radioligand [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RDWPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50150105(CHEMBL124069 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of 5HT transporter (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93BWXPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50150105(CHEMBL124069 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition constant against serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WZ9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50150105(CHEMBL124069 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition concentration against [3H]-5-HT uptake by human serotonin transporter in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RDWPubMed