Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50337914'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337914((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)propan-1...)copy SMILEScopy InChI
Affinity DataIC50: 355nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337914((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)propan-1...)copy SMILEScopy InChI
Affinity DataIC50: 657nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337914((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)propan-1...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Inhibition of [3H]serotonin reuptake at human recombinant SERT expressed in LLC-PK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J2PPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337914((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)propan-1...)copy SMILEScopy InChI
Affinity DataIC50: 709nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent