Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Sortilin' and Ligand = 'BDBM50445046'
TargetSortilin(Homo sapiens (Human))
H. Lundbeck A/S

US Patent
LigandPNGBDBM50445046(CHEMBL3098761 | US10195186, Example 24 | US9682967...)copy SMILEScopy InChI
Affinity DataKi:  2.29E+3nM IC50: 2.40E+3nMpH: 7.4Assay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22805SCUS Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck A/S

US Patent
LigandPNGBDBM50445046(CHEMBL3098761 | US10195186, Example 24 | US9682967...)copy SMILEScopy InChI
Affinity DataKi:  2.29E+3nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474CZWUS Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck A/S

US Patent
LigandPNGBDBM50445046(CHEMBL3098761 | US10195186, Example 24 | US9682967...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474CZWUS Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck A/S

US Patent
LigandPNGBDBM50445046(CHEMBL3098761 | US10195186, Example 24 | US9682967...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39BBPubMed