Found 4 Enz. Inhib. hit(s) with Target = 'Sphingosine kinase 1' and Ligand = 'BDBM50139649' TargetSphingosine kinase 1(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataKi: 2.70E+4nMAssay Description:Inhibition of human SK1 using D-erythro sphingosine as substrate and gamma[33P]ATP by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetSphingosine kinase 1(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataKi: 2.70E+4nMAssay Description:Antagonistic activity against (-)-noradrenaline-induced contraction of rat thoracic aorta (Alpha-1D adrenergic receptor)More data for this Ligand-Target Pair
In DepthDetails
TargetSphingosine kinase 1(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataKi: 2.70E+4nMAssay Description:Inhibition of recombinant human SphK1 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]SIP production using D-erythro-sphingo...More data for this Ligand-Target Pair
TargetSphingosine kinase 1(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataKi: 2.70E+4nMAssay Description:Inhibition of recombinant human C-terminal TEV cleavage site-fused-His6-tagged SphK1 expressed in baculovirus infected sf9 insect cells using d-eryth...More data for this Ligand-Target Pair
