Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Sphingosine kinase 1' and Ligand = 'BDBM50299323'
TargetSphingosine kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50299323((S)-2-amino-4-hydroxy-N-(4-octylphenyl)butanamide ...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of purified human SphK1 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736SB3PubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50299323((S)-2-amino-4-hydroxy-N-(4-octylphenyl)butanamide ...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5F9VPubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50299323((S)-2-amino-4-hydroxy-N-(4-octylphenyl)butanamide ...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of SPHK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5F9VPubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50299323((S)-2-amino-4-hydroxy-N-(4-octylphenyl)butanamide ...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human sphingosine kinase 1 by off chip mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94ZPPubMed