Compile Data Set for Download or QSAR
Found 16 Enz. Inhib. hit(s) with Target = 'Sphingosine kinase 2' and Ligand = 'BDBM50393642'
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of human recombinant SphK2 using NBD-sphingosine as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z16MTPubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Functional Histamine H3 receptor antagonistic activity in vitro assay on guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Competitive inhibition of human recombinant SphK2 assessed as NBD-S1P formation using NBD-Sph as substrate by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CF5PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0HV3PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of purified human SphK2 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736SB3PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z779VPubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q801KPubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged full length SphK2 expressed in baculovirus infected Sf9 cells using C17-sphingosine as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6GWGPubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of SPHK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2377BN8PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of recombinant human SPHK2 using sphingosine as substrate by ADP-Quest assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J3QPubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged SK2 expressed in baculovirus infected Sf9 insect cells using NBD-Sph as substrate m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3QZ4PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged Sphk2 (2 to 593 residues) expressed in Escherichia coli using varying level of sphingosine as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F193FGPubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of SK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736TWPPubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of SK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7KJHPubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NHJPubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of recombinant human SphK2 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate after 20 mins in presence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD144ZPubMed