Found 2 Enz. Inhib. hit(s) with Target = 'Squalene synthase' and Ligand = 'BDBM50049231' TargetSqualene synthase(Homo sapiens (Human))
University of Illinois at Urbana-Champaign
Curated by ChEMBL
University of Illinois at Urbana-Champaign
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli BL21 (DE3) cells assessed as formation of 1,10-dioic acid metabolite ...More data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
