Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Squalene synthase' and Ligand = 'BDBM50059865'
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50059865(4,8,12-trimethyl-(3E,7E)-3,7,11-tridecatrienylhydr...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Inhibitory activity against microsomal squalene synthaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75GXZPubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50059865(4,8,12-trimethyl-(3E,7E)-3,7,11-tridecatrienylhydr...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9RNV
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50059865(4,8,12-trimethyl-(3E,7E)-3,7,11-tridecatrienylhydr...)copy SMILEScopy InChI
Affinity DataIC50: 3.15E+4nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1XQP