Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Stearoyl-CoA desaturase' and Ligand = 'BDBM50306117'
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50306117(CHEMBL593352 | N-(2-hydroxy-2-phenylethyl)-6-(spir...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibition of SCD1 in human 293A cells assessed as conversion of [14C]stearate to [14C]oleate after 60 mins in presence of S9 microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WBJPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50306117(CHEMBL593352 | N-(2-hydroxy-2-phenylethyl)-6-(spir...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of SCD1 in human liver S9 microsomal fraction assessed as conversion of [14C]stearate to [14C]oleate after 60 mins at 0.4 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WBJPubMed