Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Stearoyl-CoA desaturase' and Ligand = 'BDBM50330385'
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50330385(6-(3,4-Dihydro-1'H-spiro[chromene-2,4'-piperidin]-...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of SCD1 in HEK293A cell microsomes assessed as reduction in conversion of [14C]stearic acid to [14C]oleic acid after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37CNPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50330385(6-(3,4-Dihydro-1'H-spiro[chromene-2,4'-piperidin]-...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibition of human SCD1 expressed in HEK293A cells assessed as reduction in conversion of [14C]stearic acid to [14C]oleic acid after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37CNPubMed