Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Steroid 17-alpha-hydroxylase/17,20 lyase' and Ligand = 'BDBM50063480'
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50063480((3S,10R,13S)-10,13-Dimethyl-17-[1,2,4]triazol-1-yl...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Binding affinity for Cytochrome P450 17A1 (17-alpha-hydroxypregnenolone Km=560 nM)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9H2NPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50063480((3S,10R,13S)-10,13-Dimethyl-17-[1,2,4]triazol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of rat cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9H2NPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50063480((3S,10R,13S)-10,13-Dimethyl-17-[1,2,4]triazol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of human testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9H2NPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50063480((3S,10R,13S)-10,13-Dimethyl-17-[1,2,4]triazol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:In vitro cytochrome P450 17A1 inhibition was assayed using the rapid acetic acid releasing assay (AARA), utilizing intact P450c17-expressing Escheric...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41B7PubMed