Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Synaptic vesicular amine transporter' and Ligand = 'BDBM50459617'
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459617(CHEMBL4213176)copy SMILEScopy InChI
Affinity DataKi:  652nMAssay Description:Displacement of [3H]reserpine from human VMAT2 expressed in HEK293 cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459617(CHEMBL4213176)copy SMILEScopy InChI
Affinity DataKi:  700nMAssay Description:Displacement of [3H](+)-syn-Ethyl 1-(2-(2,4-Dioxo-1,2-dihydroquinazolin-3(4H)-yl)ethyl)-4-(4-fluorophenyl)piperidine-3-carboxylate from human VMAT2 e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459617(CHEMBL4213176)copy SMILEScopy InChI
Affinity DataKi: >7.90E+3nMAssay Description:Displacement of [3H]DHTB from human VMAT2 expressed in HEK293 cell membranes incubated for 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459617(CHEMBL4213176)copy SMILEScopy InChI
Affinity DataIC50: 142nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed