Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50304850'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Biogen Idec Inc.

Curated by ChEMBL
LigandPNGBDBM50304850(1,2-dimethyl-5-(quinoxalin-6-yl)-4-(3-vinylphenyl)...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37ZKPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Biogen Idec Inc.

Curated by ChEMBL
LigandPNGBDBM50304850(1,2-dimethyl-5-(quinoxalin-6-yl)-4-(3-vinylphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37ZKPubMed