Affinity DataKi: 3nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Binding affinity of the compound against human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Binding affinity was evaluated against thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Tested for inhibitory activity against thymidylate synthase of L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 95nMAssay Description:In vitro inhibition of Lactobacillus casei Thymidylate synthase.More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of pure human thymidyllate synthase from extract of Manca human lymphoma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against thymidylate synthase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration of compound to inhibit Thymidylate synthase (TS) in L1210 cells at conc. of 200 microMMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of thymidyllate synthase in Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Evaluated for the inhibition of thymidylate synthase in L. caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Evaluated for the inhibition of thymidylate synthase in intact L1210 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against thymidylate Synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against thymidylate Synthase from human recombinant sourcesMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibitory concentration against Lactobacillus casei Thymidylate synthase (TS).More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against Escherichia coli Thymidylate synthase (TS).More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against recombinant human (rh) Thymidylate synthase (TS)More data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibitory concentration against rat Thymidylate synthase (TS)More data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory activity against thymidylate synthase in the intact L1210 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Evaluated for the inhibition of thymidylate synthesis in intact L1210 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory activity against the thymidylate synthase in the Permeabilized L1210 cellsMore data for this Ligand-Target Pair