Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Thymidylate synthase' and Ligand = 'BDBM50010239'
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50010239(CHEMBL1236538)copy SMILEScopy InChI
Affinity DataKi:  190nMAssay Description:Competitive inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate by r...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XK8H3FPubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50010239(CHEMBL1236538)copy SMILEScopy InChI
Affinity DataKi:  190nMAssay Description:Inhibition of amethopterin-resistant Lactobacillus casei thymidylate synthetase-catalyzed dTMP formation using dUMP as substrate by spectrophotometri...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55Q1KPubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50010239(CHEMBL1236538)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:The compound was evaluated for the inhibition of dTMP synthetase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MS3RSPPubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50010239(CHEMBL1236538)copy SMILEScopy InChI
Affinity DataKi:  9.39E+3nMAssay Description:Inhibition of amethopterin-resistant Lactobacillus casei thymidylate synthetase-catalyzed 5-BrdUMP dehalogenation by absorbance analysis in absence o...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55Q1KPubMed