Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Thymidylate synthase' and Ligand = 'BDBM50030820'
TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration of the compound against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9VN5PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration of the compound against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9VN5PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMpH: 7.4Assay Description:Inhibition of human thymidylate synthase at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B03FPPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei Thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against human TSMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S1835MPubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against recombinant human (rh) Thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W096N3PubMed