Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Thyroid hormone receptor beta' and Ligand = 'BDBM18887'
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18887(3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9k | 3-[3...)copy SMILEScopy InChI
Affinity DataIC50: 190nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R20ZMSPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18887(3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9k | 3-[3...)copy SMILEScopy InChI
Affinity DataIC50: 190nM EC50:  0.120nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M906XWPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18887(3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9k | 3-[3...)copy SMILEScopy InChI
Affinity DataIC50: 190nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18887(3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9k | 3-[3...)copy SMILEScopy InChI
Affinity DataIC50: 191nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0HD8PubMed