Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Transcription factor p65' and Ligand = 'BDBM50196926'
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50196926(CHEMBL438139 | Rocaglamide | US10085988, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of biotinylated consensus sequence binding to NF-kB p65 in human HeLa nuclear extracts after 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300MMPubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50196926(CHEMBL438139 | Rocaglamide | US10085988, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of NFkappa p65 in nuclear extract of human HeLa cells assessed as blockade of NFkappa p65 binding to biotinylated-consesus sequence by ELI...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4W31PubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50196926(CHEMBL438139 | Rocaglamide | US10085988, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of NFkappa p65 isolated from nuclear extract of human HeLa cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M6621PubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50196926(CHEMBL438139 | Rocaglamide | US10085988, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QWKPubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50196926(CHEMBL438139 | Rocaglamide | US10085988, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of TNF alpha stimulated NF-KappaB p65 in human HeLa nuclear extract assessed as decrease in NF-KappaB translocation to nucleus measured af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR51FVPubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50196926(CHEMBL438139 | Rocaglamide | US10085988, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of NFkappa p65 isolated from nuclear extract of human HeLa cells assessed as blockade of binding to biotinylated consesus sequence by chem...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4QWWPubMed