Found 3 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM50159505' TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
University of Salerno
Curated by ChEMBL
University of Salerno
Curated by ChEMBL
Affinity DataIC50: 367nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol mediated current amplitude at +80 mV holding potential b...More data for this Ligand-Target Pair
In DepthDetails
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
University of Salerno
Curated by ChEMBL
University of Salerno
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as reduction in menthol-induced calcium flux incubated for 60 mins by Fluo-4 NW-d...More data for this Ligand-Target Pair
