Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM50329104'
TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50329104(CHEMBL182120 | Indole alkaloid derivative | voacan...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Antagonist activity against mouse TRPM8 expressed in T-REx HEK cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ accumula...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7QDFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50329104(CHEMBL182120 | Indole alkaloid derivative | voacan...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Antagonist at TRPM8 isolated from mouse dorsal root ganglion cells expressed in HEK T-REx cells assessed as inhibition of menthol-induced intracellul...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P11H1PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50329104(CHEMBL182120 | Indole alkaloid derivative | voacan...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Antagonist activity against mouse TRPM8 expressed in T-REx HEK cells assessed as inhibition of menthol-induced increase in intracellular Ca2+ accumul...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7QDFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50329104(CHEMBL182120 | Indole alkaloid derivative | voacan...)copy SMILEScopy InChI
Affinity DataKd:  7.94E+3nMAssay Description:Competitive antagonist at TRPM8 isolated from mouse dorsal root ganglion cells expressed in HEK T-REx cells assessed as inhibition of menthol-induced...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P11H1PubMed