Found 5 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM125059' TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal GmbH
US Patent
Gruenenthal GmbH
US Patent
Affinity DataKi: 5nMAssay Description:The FLIPR protocol consists of 2 substance additions. First the compounds to be tested (10 μM) are pipetted onto the cells and the Ca2+ influx i...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal GmbH
US Patent
Gruenenthal GmbH
US Patent
Affinity DataKi: 6.80nMAssay Description:Displacement of [3H]-resiniferatoxin from human TRPV1 expressed in CHO cells incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal GmbH
US Patent
Gruenenthal GmbH
US Patent
Affinity DataKi: 6.80nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cell membranes after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal GmbH
US Patent
Gruenenthal GmbH
US Patent
Affinity DataKi: 12nMAssay Description:Displacement of [3H]MPOU from human TRPV1 expressed in CHO cell membranes after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal GmbH
US Patent
Gruenenthal GmbH
US Patent
Affinity DataKi: 13nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced 45Ca2+ uptake incubated for 5 mins by liquid sc...More data for this Ligand-Target Pair
