Found 4 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM176563' TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Gruenenthal GmbH
US Patent
Gruenenthal GmbH
US Patent
Affinity DataKi: 5.10nMAssay Description:The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal GmbH
US Patent
Gruenenthal GmbH
US Patent
Affinity DataKi: 26.5nM ΔG°: -45.0kJ/moleT: 2°CAssay Description:The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal GmbH
US Patent
Gruenenthal GmbH
US Patent
Affinity DataKi: 27nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced intracellular calcium level preincubated for 6 ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal GmbH
US Patent
Gruenenthal GmbH
US Patent
Affinity DataIC50: 2.59E+3nMT: 2°CAssay Description:The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...More data for this Ligand-Target Pair
