Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 4' and Ligand = 'BDBM50505550'
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50505550(CHEMBL4439190 | US11260049, Ex. 2)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human TRPV4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N30173PubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50505550(CHEMBL4439190 | US11260049, Ex. 2)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5KD5PubMed
LigandPNGBDBM50505550(CHEMBL4439190 | US11260049, Ex. 2)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at rat TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5KD5PubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50505550(CHEMBL4439190 | US11260049, Ex. 2)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85C9ZUS Patent