Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 4' and Ligand = 'BDBM50521183'
LigandPNGBDBM50521183(CHEMBL4461475 | US11260049, Ex. 125)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at human TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5KD5PubMed
LigandPNGBDBM50521183(CHEMBL4461475 | US11260049, Ex. 125)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Antagonist activity at rat TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5KD5PubMed
LigandPNGBDBM50521183(CHEMBL4461475 | US11260049, Ex. 125)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85C9ZUS Patent