Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Transitional endoplasmic reticulum ATPase' and Ligand = 'BDBM50248767'
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))TBA
LigandPNGBDBM50248767(1-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrol...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of His6-tagged p97 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ATPase activity measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2T24PubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))TBA
LigandPNGBDBM50248767(1-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrol...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of p97 in human HeLa cells assessed as reduction in proteasomal turnover of p97-dependent reporter substrate UbG76V-GFP incubated for 120 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2T24PubMed