Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Transporter' and Ligand = 'BDBM50099288'
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099288((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Ability to inhibit high affinity uptake of norepinephrine transporter into the nerve endings of rat synaptosomes using [3H]NE radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513ZXBPubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099288((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...)copy SMILEScopy InChI
Affinity DataKi:  252nMAssay Description:Ability to inhibit high affinity uptake of [3H]NE at Norepinephrine transporter (NET) using rat brain parietal/occipital cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779GMPubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099288((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...)copy SMILEScopy InChI
Affinity DataKi:  252nMAssay Description:Displacement of [3H]NE from Norepinephrine transporter of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P6114PubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099288((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...)copy SMILEScopy InChI
Affinity DataIC50: 252nMAssay Description:Inhibition of rat brain NET assessed as reduction of [3H]-NE re-uptake preincubated for 30 mins followed by [3H]-NE addition measured after 5 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7K8MPubMed