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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'Tryptophan 2,3-dioxygenase' and Ligand = 'BDBM370419'
Target
Tryptophan 2,3-dioxygenase
(Homo sapiens (Human))
Genentech
Curated by
ChEMBL
Ligand
BDBM370419
(2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol | US1023...)
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Affinity Data
IC50: 20nM
Assay Description:
Inhibition of recombinant human TDO using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2RR22JS
PubMed