Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Tumor necrosis factor' and Ligand = 'BDBM14361'
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human MNC suspension after 20 hrs by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6441PubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In DepthDetails
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6441PubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:TNF-alpha production in PBMC by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1Q46PubMed