Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Tumor necrosis factor' and Ligand = 'BDBM50552368'
TargetTumor necrosis factor(Homo sapiens (Human))TBA
LigandPNGBDBM50552368(CHEMBL4787001)copy SMILES
Affinity DataIC50: 17nMAssay Description:Displacement of fluorescent labeled probe from human recombinant His-tagged TNFalpha (77 to 233 residues) expressed in Escherichia coli preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTumor necrosis factor(Homo sapiens (Human))TBA
LigandPNGBDBM50552368(CHEMBL4787001)copy SMILES
Affinity DataIC50: 110nMAssay Description:Inhibition of exogenous human TNFalpha in HEK-Blue-CD40L cells assessed as reduction in TNF-alpha-induced NFkappaB activation incubated for 18 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB