Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Type-2 angiotensin II receptor' and Ligand = 'BDBM50236697'
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50236697(5-L-isoleucineangiotensin II | 5-isoleucine-angiot...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0BT6PubMed
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50236697(5-L-isoleucineangiotensin II | 5-isoleucine-angiot...)copy SMILEScopy InChI
Affinity DataKi:  0.898nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J67K0BUS Patent
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50236697(5-L-isoleucineangiotensin II | 5-isoleucine-angiot...)copy SMILEScopy InChI
Affinity DataIC50: 0.0800nMAssay Description:Displacement of [125I]CGP 42112A from human recombinant AT2 receptor expressed in HEK293 cells measured after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9S3SPubMed
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50236697(5-L-isoleucineangiotensin II | 5-isoleucine-angiot...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J67K0BUS Patent