Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1' and Ligand = 'BDBM50345720'
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Washington Through its Center for Commercialization

US Patent
LigandPNGBDBM50345720(1-(1-(methylsulfonyl)piperidin-4-yl)-3-(naphthalen...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MVCUS Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Washington Through its Center for Commercialization

US Patent
LigandPNGBDBM50345720(1-(1-(methylsulfonyl)piperidin-4-yl)-3-(naphthalen...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Kinase phosphorylation reactions were performed in a buffered medium containing 20 mM HEPES pH 7.5 (KOH), 0.1% BSA, 10 mM MgCl2, 1 mM EGTA (pH 7.2), ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K077GQUS Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Washington Through its Center for Commercialization

US Patent
LigandPNGBDBM50345720(1-(1-(methylsulfonyl)piperidin-4-yl)-3-(naphthalen...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D79DSFUS Patent