Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1' and Ligand = 'BDBM50556597'
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))TBA
LigandPNGBDBM50556597(CHEMBL4756586)copy SMILES
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of C-terminal NanoLuc-fused full length non-phosphorylated ABL1 (unknown origin) expressed in HEK293T cells after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5CGWPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))TBA
LigandPNGBDBM50556597(CHEMBL4756586)copy SMILES
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of C-terminal NanoLuc-fused full length non-phosphorylated ABL1 Q252H mutant (unknown origin) expressed in HEK293T cells after 2 hrs by Na...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5CGWPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))TBA
LigandPNGBDBM50556597(CHEMBL4756586)copy SMILES
Affinity DataKd:  130nMAssay Description:Inhibition of wild-type human non-phosphorylated ABL1 (S229 to K512 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5CGWPubMed