Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM191605'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Pharmacyclics LLC

US Patent
LigandPNGBDBM191605(US9181263, 14 | US9278100, 14)copy SMILEScopy InChI
Affinity DataIC50: 0.390nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 uM ATP.). Reaction condition...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4TMXUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Pharmacyclics LLC

US Patent
LigandPNGBDBM191605(US9181263, 14 | US9278100, 14)copy SMILEScopy InChI
Affinity DataIC50: 0.390nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 μM ATP.). For enzyme in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765D5ZUS Patent