Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM246413'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM246413(US9446130, 16 | US9718828, Example, 562)copy SMILEScopy InChI
Affinity DataIC50: 0.450nMAssay Description:Assay Method B: BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806H6US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM246413(US9446130, 16 | US9718828, Example, 562)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H9977TUS Patent