Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM267867'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM267867(4-(8-amino-3-{(3R)-1-[(3-methyloxetan-3-yl)carbony...)copy SMILEScopy InChI
Affinity DataIC50: 0.710nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B065BPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM267867(4-(8-amino-3-{(3R)-1-[(3-methyloxetan-3-yl)carbony...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H9977TUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM267867(4-(8-amino-3-{(3R)-1-[(3-methyloxetan-3-yl)carbony...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of BTK in human PBMC assessed as reduction in cell surface CD69 expression preincubated for 1 hr followed by stimulation with goat anti-hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B065BPubMed