Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM288531'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck & Co Inc

Curated by ChEMBL
LigandPNGBDBM288531((1R,3R,5S,6r)-3-[8- amino-1-(4-{[4- (trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867K5PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck & Co Inc

Curated by ChEMBL
LigandPNGBDBM288531((1R,3R,5S,6r)-3-[8- amino-1-(4-{[4- (trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0WJCUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck & Co Inc

Curated by ChEMBL
LigandPNGBDBM288531((1R,3R,5S,6r)-3-[8- amino-1-(4-{[4- (trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20867K5PubMed