Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM324288'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM324288((R)-1-(tert-butyl)-N-(2-(2-methoxyethyl)-8-(2-((1-...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B641CPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM324288((R)-1-(tert-butyl)-N-(2-(2-methoxyethyl)-8-(2-((1-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V69MP8US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM324288((R)-1-(tert-butyl)-N-(2-(2-methoxyethyl)-8-(2-((1-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GH9N29US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM324288((R)-1-(tert-butyl)-N-(2-(2-methoxyethyl)-8-(2-((1-...)copy SMILEScopy InChI
Affinity DataIC50: 505nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M681DUS Patent