Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM340085'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme B.V.

US Patent
LigandPNGBDBM340085(US10239883, Example 24 | US10934296, Example 24 | ...)copy SMILEScopy InChI
Affinity DataEC50:  505nMAssay Description:Btk enzyme (His-Btk (Millipore catalog #14-552), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DPQUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme B.V.

US Patent
LigandPNGBDBM340085(US10239883, Example 24 | US10934296, Example 24 | ...)copy SMILEScopy InChI
Affinity DataEC50:  55nMAssay Description:Btk enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Btk enzyme (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27947T2US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme B.V.

US Patent
LigandPNGBDBM340085(US10239883, Example 24 | US10934296, Example 24 | ...)copy SMILEScopy InChI
Affinity DataEC50:  55nMAssay Description:Btk enzyme (His-Btk (Millipore catalog #14-552), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9RQ4US Patent