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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM340112'
Target
Tyrosine-protein kinase BTK
(Homo sapiens (Human))
Merck Sharp & Dohme B.V.
US Patent
Ligand
BDBM340112
((S)-N-(1-(8-amino-1-(4-(pyridin-2- ylcarbamoyl)phe...)
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Affinity Data
EC50: <100nM
Assay Description:
Btk enzyme (His-Btk (Millipore catalog #14-552), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM D...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2GX4DPQ
US Patent