Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM499811'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)copy SMILES
Affinity DataIC50: 0.390nMAssay Description:Inhibition of wild type human BTK C481S mutant using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]ATP by radiometric assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)copy SMILES
Affinity DataIC50: 0.390nMMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)copy SMILES
Affinity DataIC50: 0.850nMMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)copy SMILES
Affinity DataIC50: 0.850nMMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)copy SMILES
Affinity DataIC50: 0.850nMAssay Description:Enzyme assay using full length recombinant active form of wild-type BTK and BTK-C481S was measured as described previously (Anastassiadis T, et al., ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)copy SMILES
Affinity DataIC50: 0.850nMAssay Description:Enzyme assay using full length recombinant active form of wild-type BTK and BTK-C481S was measured as described previously (Anastassiadis T, et al., ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)copy SMILES
Affinity DataIC50: 0.850nMAssay Description:Inhibition of wild type human BTK using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]ATP by radiometric assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)copy SMILES
Affinity DataIC50: 12.5nMMore data for this Ligand-Target Pair