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Compile Data Set for Download or QSAR
Found
2
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK [C481S]' and Ligand = 'BDBM499811'
Target
Tyrosine-protein kinase BTK [C481S]
(Homo sapiens (Human))
ArQule, Inc.
US Patent
Ligand
BDBM499811
(US11020398, Compound I-123 | US20230364079, Exampl...)
copy SMILES
Affinity Data
IC50: 0.390nM
Assay Description:
Enzyme assay using full length recombinant active form of wild-type BTK and BTK-C481S was measured as described previously (Anastassiadis T, et al., ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ0CFC
US Patent
PDB
3D Structure (crystal)
Target
Tyrosine-protein kinase BTK [C481S]
(Homo sapiens (Human))
ArQule, Inc.
US Patent
Ligand
BDBM499811
(US11020398, Compound I-123 | US20230364079, Exampl...)
copy SMILES
Affinity Data
IC50: 5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
In Depth
Details
PDB
3D Structure (crystal)