Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Fyn' and Ligand = 'BDBM4552'
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Center for Molecular Medicine of the Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FYNMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z15R6PubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Center for Molecular Medicine of the Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of Fyn dependent cellular proliferationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0MQXPubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Center for Molecular Medicine of the Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataKd:  11nMAssay Description:Binding constant for FYN kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed