Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ITK/TSK' and Ligand = 'BDBM50022937'
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022937(CHEMBL3298293)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J7TPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022937(CHEMBL3298293)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J7TPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022937(CHEMBL3298293)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as reduction in PLC-gamma phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J7TPubMed