Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ITK/TSK' and Ligand = 'BDBM50443178'
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443178(CHEMBL3086537)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443178(CHEMBL3086537)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed