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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM147774'
Target
Tyrosine-protein kinase JAK1
(Homo sapiens (Human))
Merck Sharp & Dohme Corp.
US Patent
Ligand
BDBM147774
(US8962608, 28-93)
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Affinity Data
IC50: 0.0600nM
Assay Description:
The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Ligand Info
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2J101W0
US Patent